Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 945
interventional 760
Observational 174
Registry 11

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 275
Drug|placebo 165
Behavioral 148
Device 51
Other 49
Behavioral|Other 13
Behavioral|Drug 11
Procedure 6
Biological 4
Dietary Supplement 4
Device|Other 3
Dietary Supplement|placebo 3
Drug|Other 3
Drug|Other|placebo 3
Drug|Procedure 3
Behavioral|Device 2
Behavioral|Drug|placebo 2
Dietary Supplement|Drug 2
Other|placebo 2
Behavioral|Device|Drug 1
Behavioral|Drug|Other 1
Behavioral|Other|Radiation 1
Behavioral|Procedure 1
Biological|Device 1
Combination Product 1
Combination Product|placebo 1
Device|Drug 1
Diagnostic Test 1
Dietary Supplement|Drug|placebo 1
Other|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 428
NA 58
Canada 40
Denmark 17
France 14
Brazil 13
China 12
United Kingdom 12
Australia 11
Germany 9
Spain 9
Japan 8
Taiwan 7
Korea, Republic of 6
Norway 6
Sweden 5
Israel 4
Turkey 4
United States|Canada 4
China|Japan|Korea, Republic of|Taiwan 3
India 3
Singapore 3
Belgium 2
Iran, Islamic Republic of 2
Ireland 2
Netherlands 2
Pakistan 2
Switzerland 2
United States|Austria|Canada|Colombia|Czech Republic|Germany|Guatemala|Peru|Russian Federation|Slovakia|South Africa|Ukraine|Venezuela 2
United States|Colombia|Philippines|Ukraine 2
United States|Puerto Rico 2
Argentina|Brazil|Chile|Colombia|Guatemala|Mexico|Peru|Turkey|Venezuela 1
Australia|Greece|Hungary|Russian Federation 1
Austria 1
Austria|Czech Republic|France|Germany|Greece|Hungary|Italy|Poland|Romania|Russian Federation|South Africa|Spain|Turkey 1
Bahrain|Kuwait|Oman|Qatar 1
Belgium|Germany|Hungary|Spain 1
Bulgaria 1
Canada|Colombia|Czech Republic|France|India|Lithuania|Romania|Russian Federation|Serbia|Slovakia|South Africa|Ukraine 1
Canada|Croatia|Estonia|Germany|Indonesia|Korea, Republic of|Latvia|Lithuania|Malaysia|Norway|Philippines|Poland|Russian Federation|Serbia|Taiwan|Ukraine 1
Chile 1
China|Colombia|Germany|Greece|India|Indonesia|Jordan|Lebanon|Malaysia|Mexico|Peru|Philippines|Russian Federation|South Africa|Taiwan 1
China|Japan|Korea, Republic of 1
Colombia 1
Croatia 1
Czech Republic|France|Poland|Slovakia|Spain 1
Ethiopia 1
France|Switzerland 1
Germany|Spain|Brazil|Bulgaria|United States|Argentina|Belgium 1
Hong Kong|Philippines|Taiwan|Thailand 1
Ireland|United Kingdom 1
Israel|Romania 1
Italy 1
Japan|Lithuania|Malaysia|Philippines|Russian Federation|Slovakia|Taiwan|Ukraine 1
Macedonia, The Former Yugoslav Republic of 1
Mexico 1
Montenegro 1
Netherlands|Spain 1
Poland 1
Russian Federation|Belgium|Bulgaria|Germany|India|Israel|Poland|South Africa|Ukraine 1
Uganda 1
United States|Argentina|Bulgaria|Colombia|India|Lithuania|Malaysia|Mexico|Peru|Philippines|Romania|Russian Federation|Taiwan|Thailand|Ukraine 1
United States|Australia 1
United States|Australia|Bulgaria|Czech Republic|Estonia|France|Germany|Hungary|Italy|Netherlands|Poland|Portugal|Russian Federation|South Africa|Spain|Switzerland|United Kingdom 1
United States|Australia|Chile|Colombia|Costa Rica|Greece|Mexico|Peru|Romania|South Africa|Turkey 1
United States|Australia|India 1
United States|Austria|India|Malaysia|Poland|Russian Federation|Slovakia|Spain|Taiwan|Ukraine 1
United States|Belgium|Germany|Greece|Netherlands|Poland 1
United States|Brazil|Bulgaria|Croatia|Czech Republic|France|India|Russian Federation|South Africa 1
United States|Bulgaria|Canada|Colombia|Russian Federation|Ukraine 1
United States|Bulgaria|China|Costa Rica|France|Germany|India|Malaysia|Panama|Poland|Romania|Russian Federation|Serbia|South Africa|Turkey|Ukraine 1
United States|Bulgaria|Colombia|France|Hungary|Korea, Republic of|Malaysia|Mexico|Philippines|Poland|Puerto Rico|Romania|Russian Federation|Spain|Ukraine 1
United States|Bulgaria|Colombia|Russian Federation|Serbia|Ukraine 1
United States|Bulgaria|Croatia|Mexico|Peru|Russian Federation|South Africa 1
United States|Bulgaria|Croatia|Puerto Rico|Romania|Serbia|Slovakia|Ukraine 1
United States|Bulgaria|Estonia|Lithuania|Poland|Puerto Rico 1
United States|Bulgaria|Poland|Serbia 1
United States|Bulgaria|Russian Federation|Serbia|Ukraine 1
United States|Canada|Colombia|Czech Republic|France|India|Japan|Lithuania|Peru|Poland|Romania|Russian Federation|Slovakia|South Africa|Ukraine 1
United States|Canada|Colombia|Czech Republic|India|Japan|Lithuania|Peru|Slovakia|Ukraine 1
United States|Canada|Germany|Israel 1
United States|Canada|Japan|United Kingdom 1
United States|Canada|Mexico|Netherlands|Puerto Rico 1
United States|Chile|France|Germany|Guatemala|Hong Kong|India|Italy|Mexico|Russian Federation|Spain|Taiwan|Venezuela 1
United States|Colombia|India|Mexico|Serbia|South Africa|Taiwan 1
United States|Croatia|Romania|Russian Federation|Serbia|Ukraine 1
United States|Croatia|Ukraine 1
United States|Czech Republic|France|Germany|India|Poland|Romania|Russian Federation|South Africa|Ukraine 1
United States|Czech Republic|France|India|Romania|Russian Federation|South Africa|Ukraine 1
United States|France|Russian Federation 1
United States|Germany 1
United States|Greece|Korea, Republic of|Lithuania|Russian Federation|Taiwan|Turkey|Ukraine 1
United States|India 1
United States|Israel 1
United States|Lithuania|Puerto Rico|Romania|Russian Federation 1
United States|Puerto Rico|Russian Federation 1
United States|Russian Federation 1

Sites per Study

Site_count Study_Count
1 530
2 55
3 25
4 19
5 9
6 6
7 4
8 2
9 2
10 4
11 7
12 4
13 5
14 1
15 1
16 6
17 3
18 1
19 2
20 1
21 4
22 2
24 3
26 1
27 2
28 2
29 2
31 1
32 2
34 1
36 1
38 2
40 1
41 1
42 1
43 1
44 2
45 1
46 2
47 2
48 2
50 2
51 1
52 2
53 1
54 1
55 3
60 1
64 1
65 1
66 2
67 2
70 1
71 2
73 2
74 1
75 1
76 1
80 1
83 1
88 2
89 1
91 1
94 1
95 1
98 1
108 1
151 1
308 1

Phase

Phase Study_Count
N/A 288
Phase 3 173
Phase 4 162
Phase 2 70
Phase 1 37
Phase 2/Phase 3 14
Phase 1/Phase 2 11
Early Phase 1 5

Number of Arms

Number_of_Arms Count_of_Studies
1 119
2 402
3 71
4 21
5 4
6 4
8 2
10 1
NA 136

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 2.0 5.0000 8.00000 5.00000 2.000 8.0000 8.0000 1.0000
1st Qu. 3.0 35.0000 22.25000 14.00000 39.500 62.0000 60.0000 30.0000
Median 9.0 61.0000 38.50000 38.00000 60.000 77.5000 193.0000 57.0000
Mean 35.6 180.8889 48.22222 45.54545 1553.059 115.3571 246.3787 128.5556
3rd Qu. 20.0 144.5000 57.25000 59.00000 91.750 119.7500 381.0000 130.0000
Max. 144.0 10347.0000 305.00000 152.00000 100000.000 431.0000 1255.0000 1800.0000

Trial Group Type

group_type Group_Count
Experimental 612
Active Comparator 304
Placebo Comparator 213
NA 136
No Intervention 80
Other 60
Sham Comparator 21

Intervention Model

intervention_model Study_Count
Parallel Assignment 513
Single Group Assignment 167
Crossover Assignment 48
NA 17
Factorial Assignment 13
Sequential Assignment 2

Primary Purpose

primary_purpose Study_Count
Treatment 615
Prevention 28
Health Services Research 27
Other 25
Basic Science 23
Supportive Care 18
NA 14
Diagnostic 8
Device Feasibility 1
Screening 1

Observational Studies

Studies by Country

Country Study_Count
United States 84
NA 19
Spain 11
Canada 8
France 6
Norway 5
United Kingdom 5
China 4
Korea, Republic of 4
Greece 3
Israel 3
Belgium 2
Switzerland 2
Turkey 2
Austria 1
Austria|Belgium|Brazil|France|Germany|Portugal|Romania|Turkey|Ukraine|Venezuela 1
Belgium|Croatia|Denmark|Finland|Germany|Italy|Turkey|United Kingdom 1
Croatia 1
Denmark 1
Egypt 1
France|Germany|Greece 1
Hong Kong 1
Italy 1
Japan 1
Netherlands 1
Romania 1
Russian Federation 1
United States|Canada 1
United States|Canada|Israel|Singapore|United Kingdom 1
United States|Canada|Norway 1

Sites per Study

Site_count Study_Count
1 129
2 15
3 3
5 1
6 3
10 1
14 1
16 1
19 1
20 2
23 1
24 2
25 1
30 1
32 1
33 1
34 2
35 1
46 1
47 1
49 1
52 1
57 1
86 1
213 1

Enrollment Metrics

Measure Observational
Min 4.00
1st Qu 60.50
Median 182.00
Mean 11681.28
3rd Qu 598.75
Max 751725.00

Observation Model

observational_model Study_Count
Cohort 65
NA 31
Case-Only 28
Case-Control 21
Case Control 11
Other 8
Ecologic or Community 5
Case-Crossover 2
Family-Based 2
Defined Population, Natural History 1

Time Perspective

time_perspective Study_Count
Prospective 98
Cross-Sectional 33
Retrospective 21
NA 15
Other 6
Cross-Sectional, Prospective 1

Registries

Studies by Country

Country Study_Count
United States 5
France 2
Canada 1
Korea, Republic of 1
Poland 1
Sweden 1

Sites per Study

Site_count Study_Count
1 11

Enrollment Metrics

Measure Registries
Min 10.00
1st Qu 175.00
Median 500.00
Mean 67272.36
3rd Qu 4108.00
Max 700000.00

Registry Model

observational_model Study_Count
Cohort 7
Case-Control 2
Family-Based 1
Other 1

Time Perspective

time_perspective Study_Count
Prospective 7
Other 3
Cross-Sectional 1

Follow-up

target_duration Study_Count
1 Year 2
2 Years 2
1 Day 1
1 Week 1
10 Years 1
15 Months 1
2 Weeks 1
3 Years 1
6 Months 1

Overview of Studies

Interventional Trials

#If less then 500 trials

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT04209296 Chart Review of Patients Undergoing Ketamine Infusions https://ClinicalTrials.gov/show/NCT04209296 Active, not recruiting Brain and Cognition Discovery Foundation 2020-12-03
NCT03360942 Long Term Follow-up of Deep Brain Stimulation for Treatment-Resistant Depression https://ClinicalTrials.gov/show/NCT03360942 Active, not recruiting Dartmouth-Hitchcock Medical Center 2026-11-22
NCT03336918 Lithium Effects on the Brain’s Functional and Structural Connectome in the Treatment of Bipolar Disorder https://ClinicalTrials.gov/show/NCT03336918 Recruiting The Cleveland Clinic 2021-08-01
NCT03245593 Shared Medical Decision Making in the Prophylactic Treatment of Bipolar Disorder https://ClinicalTrials.gov/show/NCT03245593 Recruiting Centre Hospitalier Universitaire de Nīmes 2021-01-31
NCT03235908 Copeptin in Outcome Prediction of an Acute Psychotic Episode https://ClinicalTrials.gov/show/NCT03235908 Active, not recruiting University Hospital, Basel, Switzerland 2020-07-31
NCT03181698 Brain Voxel-based Morphometry in Bipolar Mania https://ClinicalTrials.gov/show/NCT03181698 Completed Assiut University 2018-07-14
NCT03166098 The Role of Dysmyelination in Cognitive Impairment of Psychotic Spectrum Disorders https://ClinicalTrials.gov/show/NCT03166098 Active, not recruiting NYU Langone Health 2020-11-30
NCT03162380 Occupational Stress and Bipolar Disorder https://ClinicalTrials.gov/show/NCT03162380 Completed University Hospital, Montpellier 2018-05-31
NCT03131505 INCLUDE: Using Lived Experience to Improve Mental Health Diagnosis v1 https://ClinicalTrials.gov/show/NCT03131505 Completed Norfolk and Suffolk NHS Foundation Trust 2017-12-01
NCT03127176 Dysbiosis in Bipolar Disorder https://ClinicalTrials.gov/show/NCT03127176 Recruiting Hospital Clinic of Barcelona 2021-06-30
NCT02978534 Pharmacokinetics of Quetiapine Across Pregnancy and Postpartum https://ClinicalTrials.gov/show/NCT02978534 Active, not recruiting Northwestern University 2020-08-31
NCT02970721 Use of Psychotropic Medications Among Pregnant Women With Bipolar Disorder https://ClinicalTrials.gov/show/NCT02970721 Completed Western University, Canada 2018-05-31
NCT02888262 The Bipolar Illness Onset Study (the BIO Study) https://ClinicalTrials.gov/show/NCT02888262 Recruiting Mental Health Services in the Capital Region, Denmark 2026-12-31
NCT02804867 Spot Depression Study https://ClinicalTrials.gov/show/NCT02804867 Completed University of Cambridge 2016-09-30
NCT02773108 Somatic Comorbidities in Psychiatric Patients https://ClinicalTrials.gov/show/NCT02773108 Completed Sveti Ivan Psychiatric Hospital 2016-06-30
NCT02760693 Bipolar Cohort Neunkirchen, Final Statement https://ClinicalTrials.gov/show/NCT02760693 Completed Österreichische Gesellschaft für Bipolare Erkrankungen 2016-03-31
NCT02756065 Connectomics in Psychiatric Classification of Bipolar Disorder and Schizophrenia https://ClinicalTrials.gov/show/NCT02756065 Recruiting Washington University Early Recognition Center 2019-06-30
NCT02746367 Bipolar Proteomic Assay Validation Study https://ClinicalTrials.gov/show/NCT02746367 Completed Myriad Genetic Laboratories, Inc. 2018-11-08
NCT02742064 Quantified Mobile Sensing for Improving Diagnosis and Measuring Disease Progression https://ClinicalTrials.gov/show/NCT02742064 Completed Cogito Health Inc 2017-12-31
NCT02739932 Adolescent Mental Health: Canadian Psychiatric Risk and Outcome Study https://ClinicalTrials.gov/show/NCT02739932 Active, not recruiting University of Calgary 2021-08-31
NCT02727127 Brain Ion Homeostasis, Lithium and Bipolar Disorder https://ClinicalTrials.gov/show/NCT02727127 Recruiting NYU Langone Health 2019-09-30
NCT02637401 Group Dialectical Behavioural Therapy for Mood Instability Within Bipolar Disorder: An Open Trial https://ClinicalTrials.gov/show/NCT02637401 Completed University of Exeter 2016-01-31
NCT02596698 Mitochondrial Dysfunction, Inflammation, and White Matter Integrity in Youth With Mood Disorders https://ClinicalTrials.gov/show/NCT02596698 Completed University of Minnesota 2018-03-31
NCT02582736 Antipsychotics and Risk of Hyperglycemic Emergencies https://ClinicalTrials.gov/show/NCT02582736 Completed Canadian Network for Observational Drug Effect Studies, CNODES 2012-12-31
NCT00001174 Evaluation of the Genetics of Bipolar Disorder https://ClinicalTrials.gov/show/NCT00001174 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT03403790 A Survey on Quetiapine Extended-release Tablets in Patients With Depression in Bipolar Disorder https://ClinicalTrials.gov/show/NCT03403790 Completed Astellas Pharma Inc 2020-03-19
NCT02560701 High Deductible Health Plans and Bipolar Disorder https://ClinicalTrials.gov/show/NCT02560701 Completed Harvard Pilgrim Health Care 2018-02-28
NCT03017781 A Study of the Relationship of Psychosocial Function With Mood Symptoms in Offspring of Parents With Bipolar Disorder https://ClinicalTrials.gov/show/NCT03017781 Active, not recruiting Janssen Research & Development, LLC 2021-04-30
NCT00006177 Child & Adolescent Bipolar Disorder Brain Imaging and Treatment Study https://ClinicalTrials.gov/show/NCT00006177 Completed National Institutes of Health Clinical Center (CC) NA
NCT02505022 Role Functioning Changes NOS https://ClinicalTrials.gov/show/NCT02505022 Recruiting Northwestern University 2021-01-31
NCT02490241 Lithium Therapy: Understanding Mothers, Metabolism and Mood https://ClinicalTrials.gov/show/NCT02490241 Active, not recruiting Northwestern University 2019-12-31
NCT02476877 A Pilot, Proof-of-concept Cohort Study of the Prevalence of Comorbid Mental Illness and Substance Abuse https://ClinicalTrials.gov/show/NCT02476877 Completed Advanced Clinical Laboratory Solutions, Inc. 2016-01-31
NCT02423499 Features Emotional Responses in Adults With Autism: Comparison With Bipolar Disorder (REMBAU) https://ClinicalTrials.gov/show/NCT02423499 Completed University Hospital, Tours 2019-05-26
NCT02418910 Effectiveness of Two Self Assessment Tools: KIOS-Bipolar or eMoods https://ClinicalTrials.gov/show/NCT02418910 Completed The University of Texas Health Science Center at San Antonio 2017-04-30
NCT02374996 Pharmacoepigenetics of Bipolar Disorder Treatment https://ClinicalTrials.gov/show/NCT02374996 Completed Wayne State University 2017-09-30
NCT02330068 Microbiome of Depression & Treatment Response to Citalopram https://ClinicalTrials.gov/show/NCT02330068 Completed Mayo Clinic 2017-12-31
NCT02323763 An fMRI Study on Temporal Discounting in Bipolar Disorder https://ClinicalTrials.gov/show/NCT02323763 Completed Massachusetts General Hospital 2016-08-29
NCT02242669 Enhancing Outcomes, Reducing Costs: Evaluating Peer Support for Mood Disorders https://ClinicalTrials.gov/show/NCT02242669 Completed Massachusetts General Hospital 2017-04-30
NCT02083978 Bipolar Research Study Using MR Imaging https://ClinicalTrials.gov/show/NCT02083978 Completed Washington University Early Recognition Center 2014-12-31
NCT01315509 Dental Status of Patients With Severe Mental Illness https://ClinicalTrials.gov/show/NCT01315509 Completed Hadassah Medical Organization 2012-09-30
NCT01282281 Prospective Metabolic Monitoring of Youth and Adults With Bipolar Disorder https://ClinicalTrials.gov/show/NCT01282281 Completed Sunnybrook Health Sciences Centre 2013-01-31
NCT01272531 Pharmacogenomics of Mood Stabilizer Response in Bipolar Disorder (PGBD) https://ClinicalTrials.gov/show/NCT01272531 Completed University of California, San Diego 2016-04-30
NCT01269710 Second-Generation Antipsychotic Treatment Indication Effectiveness And Tolerability In Youth (Satiety) Study https://ClinicalTrials.gov/show/NCT01269710 Completed University of North Carolina, Chapel Hill 2011-03-31
NCT02048995 Neural and Visual Responses to Light in Bipolar Disorder: A Novel Putative Biomarker https://ClinicalTrials.gov/show/NCT02048995 Completed Northwestern University 2017-12-31
NCT02036606 Racing and Crowded Thoughts in Mood Disorders https://ClinicalTrials.gov/show/NCT02036606 Recruiting University Hospital, Strasbourg, France 2019-04-30
NCT02919280 Dallas 2K: A Natural History Study of Depression https://ClinicalTrials.gov/show/NCT02919280 Recruiting University of Texas Southwestern Medical Center 2026-09-30
NCT02006862 eVAluatIon of OLanzapine TreatmEnT https://ClinicalTrials.gov/show/NCT02006862 Completed Elpen Pharmaceutical Co. Inc. 2014-12-31
NCT01996293 Pregnant Women Taking Lamictal for Bipolar Disorder https://ClinicalTrials.gov/show/NCT01996293 Active, not recruiting Northwestern University 2020-08-31
NCT01992302 Risk Factors for Development of Rapid Cycling in Bipolar Disorder Patients https://ClinicalTrials.gov/show/NCT01992302 Completed Hospital Clinic of Barcelona 2013-11-30
NCT01976975 Brain Mechanisms of Human Motivation https://ClinicalTrials.gov/show/NCT01976975 Completed Mclean Hospital 2018-01-31
NCT01931644 At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions https://ClinicalTrials.gov/show/NCT01931644 Recruiting Sanguine Biosciences 2025-08-31
NCT01795326 Physician Survey on Monitoring of Patients Treated With Quetiapine https://ClinicalTrials.gov/show/NCT01795326 Completed AstraZeneca 2013-09-30
NCT01793324 EMR Data to Assess Monitoring of Patients Treated With Quetiapine https://ClinicalTrials.gov/show/NCT01793324 Completed AstraZeneca 2013-06-30
NCT01786369 Adherence in Patients Admitted to a Psychiatric Unit for Acute Psychosis: an Analysis of Serum Levels of Antipsychotics. https://ClinicalTrials.gov/show/NCT01786369 Completed Northwell Health 2015-04-30
NCT01770704 Observation Study of the Clinical Management of Bipolar Disorder https://ClinicalTrials.gov/show/NCT01770704 Completed AstraZeneca 2014-07-31
NCT01739127 Comparison of Aripiprazole Versus Higher Metabolic Risk Antipsychotic Drugs on Adiposity Using MRI https://ClinicalTrials.gov/show/NCT01739127 Completed University of British Columbia 2016-02-29
NCT01734278 Observational Post-Authorisation Safety Study of Asenapine (Sycrest) https://ClinicalTrials.gov/show/NCT01734278 Completed Drug Safety Research Unit, Southampton, UK 2017-01-31
NCT01719315 Neurophysiologic Correlates of Hypersomnia https://ClinicalTrials.gov/show/NCT01719315 Completed University of Wisconsin, Madison 2018-06-30
NCT01639482 Neuroimaging Studies of the Treatment of Bipolar Depression With Citalopram https://ClinicalTrials.gov/show/NCT01639482 Completed Massachusetts General Hospital 2013-12-31
NCT01629355 Auditory Brainstem Response as a Diagnostic Tool in Schizophrenia and Bipolar Disorder https://ClinicalTrials.gov/show/NCT01629355 Completed University Hospital of North Norway 2015-05-31
NCT01583569 Complex Dynamic Systems in Mood Disorders https://ClinicalTrials.gov/show/NCT01583569 Completed Massachusetts General Hospital 2014-06-30
NCT01503489 Risk Factors for AD-Associated Switch to Mania https://ClinicalTrials.gov/show/NCT01503489 Completed Hospital Clinic of Barcelona 2010-01-31
NCT01498770 An Observational Drug Utilization Study of Asenapine in the United Kingdom (P08308) https://ClinicalTrials.gov/show/NCT01498770 Completed Merck Sharp & Dohme Corp. 2017-12-21
NCT01495741 Post-Authorization Safety Surveillance Study of Asenapine in Participants With Bipolar Disorder (P08307) https://ClinicalTrials.gov/show/NCT01495741 Completed Merck Sharp & Dohme Corp. 2017-12-18
NCT01455961 An Epidemiological Registry Study to Evaluate Clinical Practice Treatment in Patients With Bipolar Disorder https://ClinicalTrials.gov/show/NCT01455961 Completed AstraZeneca 2012-04-30
NCT01455038 Heart Rate Variability of Patients With Bipolar Disorder in Subsyndromal Depressive Phase https://ClinicalTrials.gov/show/NCT01455038 Completed Asan Medical Center 2010-04-30
NCT01447082 General Practice Research Database Seroquel XR Safety Study https://ClinicalTrials.gov/show/NCT01447082 Completed AstraZeneca 2012-12-31
NCT01431326 Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care https://ClinicalTrials.gov/show/NCT01431326 Completed Duke University 2019-11-30
NCT01428518 Special Drug Use Investigation for LAMICTAL Bipolar https://ClinicalTrials.gov/show/NCT01428518 Completed GlaxoSmithKline 2016-01-31
NCT01395160 Female Experiences and Brain Activity https://ClinicalTrials.gov/show/NCT01395160 Completed King’s College London 2012-11-30
NCT01392482 IBIS: Italian Burden of Illness on Schizophrenia & Bipolar Disorder https://ClinicalTrials.gov/show/NCT01392482 Completed AstraZeneca 2012-09-30
NCT01385709 The Influence of the Menstrual Cycle on Lithium and Sertraline Blood Levels https://ClinicalTrials.gov/show/NCT01385709 Completed Weill Medical College of Cornell University 2012-08-31
NCT01384604 Neurophysiological Studies in Schizophrenia and Psychiatric Disorders https://ClinicalTrials.gov/show/NCT01384604 Completed University of Texas Southwestern Medical Center 2013-05-31
NCT01383915 Clinical Risk State for Bipolar Disorder in Adolescents https://ClinicalTrials.gov/show/NCT01383915 Recruiting Northwell Health 2022-12-31
NCT01377896 The Purpose of the Study is to Gain an In-depth Picture of the Patient Management and Prescription Behaviours https://ClinicalTrials.gov/show/NCT01377896 Completed AstraZeneca 2010-10-31
NCT01342380 Pioglitazone and Quetiapine XR Pharmacogenetic Study https://ClinicalTrials.gov/show/NCT01342380 Completed University Hospitals Cleveland Medical Center 2015-05-31
NCT01342120 PHARMO Institute Seroquel Safety Study https://ClinicalTrials.gov/show/NCT01342120 Completed AstraZeneca 2010-11-30
NCT01322113 Involvement of the Sodium Pump and Endogenous Digitalis-like Compounds in Bipolar Disorder https://ClinicalTrials.gov/show/NCT01322113 Completed Hadassah Medical Organization 2013-09-30
NCT04420793 Voice Changes During ECT https://ClinicalTrials.gov/show/NCT04420793 Recruiting Medical University of South Carolina 2021-06-30
NCT04304417 The Role of Group Identity on the Community Integration of People With Severe Mental Disorder https://ClinicalTrials.gov/show/NCT04304417 Recruiting Universidad Complutense de Madrid 2020-03-31
NCT04237610 Reward and Punishment Sensitivity in Bipolar Disorders https://ClinicalTrials.gov/show/NCT04237610 Recruiting University Hospital, Grenoble 2021-12-31
NCT04211428 A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Bipolar Disorder https://ClinicalTrials.gov/show/NCT04211428 Recruiting ProgenaBiome 2023-03-31
NCT04059952 Mechanism of Action of Electroconvulsive Therapy https://ClinicalTrials.gov/show/NCT04059952 Recruiting Massachusetts General Hospital 2021-06-01
NCT04034147 Clinical Determinants of the Discrepancy Between Objective and Subjective Cognition in the Versailles FACE-BD Cohort https://ClinicalTrials.gov/show/NCT04034147 Completed Versailles Hospital 2018-12-31
NCT04024553 A Genetic Family Cohort Study of Bipolar Disorder in Chinese Han Population https://ClinicalTrials.gov/show/NCT04024553 Enrolling by invitation Shanghai Mental Health Center 2020-12-31
NCT03949218 Bipolar Disorder and Oxidative Stress Injury Mechanism - Clinical Big Data Analysis Based on Machine Learning https://ClinicalTrials.gov/show/NCT03949218 Completed Shanghai Mental Health Center 2018-11-20
NCT03898297 Imaging mGluR5 and Synaptic Density in Psychiatric Disorders https://ClinicalTrials.gov/show/NCT03898297 Recruiting Yale University 2022-01-31
NCT03857438 Correlation of Audiovisual Features With Clinical Variables and Neurocognitive Functions in Bipolar Disorder, Mania https://ClinicalTrials.gov/show/NCT03857438 Completed Istanbul Saglik Bilimleri University 2017-02-20
NCT03829787 Attentional Biases, Reward Sensitivity, and Cognitive Control in Adults With Bipolar Disorder https://ClinicalTrials.gov/show/NCT03829787 Recruiting University Hospitals Cleveland Medical Center 2020-09-01
NCT03788811 ERG Components in Schizophrenia and Bipolar Disorder Type I https://ClinicalTrials.gov/show/NCT03788811 Recruiting diaMentis Inc. 2020-12-31
NCT03774641 A Pilot Study of Prophylactic Management of Lamotrigine in Pregnant Women https://ClinicalTrials.gov/show/NCT03774641 Recruiting Johns Hopkins University 2020-12-31
NCT03711045 An Eye Tracking Study of Affective Disorder Patients With Suicide Risk https://ClinicalTrials.gov/show/NCT03711045 Recruiting Central South University 2019-12-31
NCT03656302 Circadian Rhythm Dysregulation in Offspring of Parents With Bipolar Disorder https://ClinicalTrials.gov/show/NCT03656302 Recruiting Chinese University of Hong Kong 2020-02-28
NCT03638687 Neuroimaging Epigenetics of Prospective Postpartum Depression Biomarkers https://ClinicalTrials.gov/show/NCT03638687 Active, not recruiting Johns Hopkins University 2019-10-31
NCT03615794 A Study of Pregnant and Postpartum Women With and Without Mood Disorders https://ClinicalTrials.gov/show/NCT03615794 Recruiting Johns Hopkins University 2021-10-31
NCT03572426 Ion Channel Genetic Biomarkers: Diagnostic Capabilities in the Assessment of Bipolar Disorder https://ClinicalTrials.gov/show/NCT03572426 Completed University of Colorado, Denver 2019-04-04
NCT03528278 Using Motivational Techniques to Increase Levels of Physical Activity in Long Term Psychiatric Inpatient Wards https://ClinicalTrials.gov/show/NCT03528278 Completed Oslo University Hospital 2015-03-10
NCT03429361 Testing the Value of Smartphone Assessments of People With Mood Disorders https://ClinicalTrials.gov/show/NCT03429361 Completed Mindstrong 2019-05-30
NCT01263548 To Evaluate the Safety and Metabolic Profile of Vyvanse for the Treatment of ADHD in Euthymic Adults With Bipolar I/II Disorder https://ClinicalTrials.gov/show/NCT01263548 Completed University Health Network, Toronto 2012-01-31
NCT01255982 Functional Assessment of Patients With Acute Bipolar Depression After 8 Months of Follow-up https://ClinicalTrials.gov/show/NCT01255982 Completed AstraZeneca 2011-12-31
NCT01245348 Relative Effectiveness of Schizophrenia Therapy Study https://ClinicalTrials.gov/show/NCT01245348 Completed Medco Health Solutions, Inc. 2012-12-31
NCT01239589 European Study to Describe Hospital Stay in Patients Admitted for Acute Bipolar Manic Episodes https://ClinicalTrials.gov/show/NCT01239589 Completed AstraZeneca 2011-03-31
NCT01237379 Peroxisomal Defects and Familial Risk for Bipolar Disorder https://ClinicalTrials.gov/show/NCT01237379 Completed University of Cincinnati 2013-10-31
NCT01202604 A Study Evaluating the Efficacy of Administered Maintenance Treatments in Bipolar Disorder I and II. https://ClinicalTrials.gov/show/NCT01202604 Completed AstraZeneca 2011-12-31
NCT01196858 Duration of Untreated Psychosis (DUP) and Pathways to Care in Nordland https://ClinicalTrials.gov/show/NCT01196858 Completed University Hospital of North Norway 2013-09-30
NCT01181960 Research and Evaluation of Antipsychotic Treatment in Community Behavioral Health Organizations https://ClinicalTrials.gov/show/NCT01181960 Completed Janssen Scientific Affairs, LLC 2013-11-30
NCT01149551 CSP #572 - Genetics of Functional Disability in Schizophrenia and Bipolar Illness https://ClinicalTrials.gov/show/NCT01149551 Completed VA Office of Research and Development 2014-06-30
NCT01106313 Insulin Resistance in Patients With Major Depression https://ClinicalTrials.gov/show/NCT01106313 Completed Stanford University 2016-01-31
NCT01064297 Lamotrigine Pregnancy Registry (LAM05) https://ClinicalTrials.gov/show/NCT01064297 Completed GlaxoSmithKline 2010-07-31
NCT01062607 Study of the Clinical Management of Bipolar Disease https://ClinicalTrials.gov/show/NCT01062607 Completed AstraZeneca 2011-06-30
NCT01053429 A Non-Interventional Post-Marketing Surveillance Study to Evaluate the Safety and Efficacy of Zeldox Capsule https://ClinicalTrials.gov/show/NCT01053429 Completed Pfizer 2010-02-28
NCT01029145 Management of Index Episode in Patients With Bipolar Disorder Treated by Seroquel XR https://ClinicalTrials.gov/show/NCT01029145 Completed AstraZeneca 2010-05-31
NCT01028196 Observational Study to Evaluate Bipolar Disorder Symptoms in Patients Presented With Schizophrenia or Depression https://ClinicalTrials.gov/show/NCT01028196 Completed AstraZeneca 2010-11-30
NCT01012180 Parents With Bipolar Disorder: Relationship of Adaptation to Own Illness With Risk Perception and Coping With Perceived Risk to a Child https://ClinicalTrials.gov/show/NCT01012180 Completed National Institutes of Health Clinical Center (CC) NA
NCT00961935 Pediatric Bipolar Disorder Study at UCLA https://ClinicalTrials.gov/show/NCT00961935 Completed University of California, Los Angeles 2011-08-31
NCT00952757 Changes in Hyperprolactinemia Secondary to Antipsychotics After Switching to Quetiapine https://ClinicalTrials.gov/show/NCT00952757 Completed Investigaciones Médicas Montejo S.L. 2008-08-31
NCT00927420 Epidemiological Study to Evaluate Adherence to Treatment in Bipolar Disorder: Adherence Study https://ClinicalTrials.gov/show/NCT00927420 Completed AstraZeneca NA
NCT00888264 A NIS Evaluating the Treatment Patterns of Atypical Antipsychotics in Patients Diagnosed With Bipolar I or II Disorder https://ClinicalTrials.gov/show/NCT00888264 Completed AstraZeneca 2010-08-31
NCT00864370 Bipolar Disorder (BPD) in Pregnancy: Predictors of Morbidity https://ClinicalTrials.gov/show/NCT00864370 Completed Emory University 2011-01-31
NCT02675712 Effect of African Drumming in Mood Disorders https://ClinicalTrials.gov/show/NCT02675712 Completed University of Stellenbosch 2015-06-30
NCT00787930 Bipolar Disorder in Late Life https://ClinicalTrials.gov/show/NCT00787930 Completed Duke University 2010-09-30
NCT00763581 Personal Adherence Evaluation of Medication Use for Adult Bipolar Disorder Patients https://ClinicalTrials.gov/show/NCT00763581 Completed Case Western Reserve University 2008-11-30
NCT00757328 Treatment Clinical Practice in Bipolar Depression in Spain https://ClinicalTrials.gov/show/NCT00757328 Completed AstraZeneca NA
NCT00745966 Atypical Antipsychotics in Improvement of Quality of Life in Bipolar Disorder https://ClinicalTrials.gov/show/NCT00745966 Completed AstraZeneca 2008-09-30
NCT00741299 A Study of the Association Between Tobacco Smoking and Bipolar Affective Disorder https://ClinicalTrials.gov/show/NCT00741299 Completed Tirat Carmel Mental Health Center 2009-07-31
NCT00692133 Spanish Validation of Tool Questionnaire to Assess Patients´Perception About Antipsychotic Treatment https://ClinicalTrials.gov/show/NCT00692133 Completed AstraZeneca 2008-08-31
NCT00691353 Subjective Well Being of Patients Receiving Atypical Antipsychotics as Monotherapy or Cotherapy With Mood Stabilizers https://ClinicalTrials.gov/show/NCT00691353 Completed AstraZeneca 2008-07-31
NCT00690248 Depressive Symptoms in Acute Manic Episode https://ClinicalTrials.gov/show/NCT00690248 Completed AstraZeneca 2008-07-31
NCT00683709 Specialized Clozapine Clinic for Bipolar and Schizoaffective Disorder https://ClinicalTrials.gov/show/NCT00683709 Completed St. Joseph’s Healthcare Hamilton 2011-07-31
NCT00660712 Evaluation of Patient Characteristics and Treatment Approaches to Patients With Bipolar Disorder in Turkey https://ClinicalTrials.gov/show/NCT00660712 Completed AstraZeneca NA
NCT00616889 Effect of Quetiapine on Sleep Architecture in Bipolar Depression and Major Depressive Disorder https://ClinicalTrials.gov/show/NCT00616889 Completed Queen’s University 2009-01-31
NCT00609193 Functional and Neurochemical Brain Changes in First-episode Bipolar Mania https://ClinicalTrials.gov/show/NCT00609193 Completed University of Cincinnati 2015-06-30
NCT00608296 Functional and Neurochemical Brain Changes Bipolar Depression https://ClinicalTrials.gov/show/NCT00608296 Completed University of Cincinnati 2013-07-31
NCT00592267 Screening Protocol for Children and Adolescents With Bipolar and Bipolar Spectrum Disorder https://ClinicalTrials.gov/show/NCT00592267 Recruiting Massachusetts General Hospital 2020-12-31
NCT00585702 Antimanic Drug Use in Pregnancy https://ClinicalTrials.gov/show/NCT00585702 Completed University of Pittsburgh 2012-03-31
NCT00585273 Antipsychotics and Blood Vessel Function https://ClinicalTrials.gov/show/NCT00585273 Completed University of Iowa 2014-11-30
NCT00584961 BIMET Study: Evolution of Metabolic and Cardiovascular Risks Factors in Patients With Bipolar Disorder https://ClinicalTrials.gov/show/NCT00584961 Completed Pfizer 2009-02-28
NCT00580268 Bipolar Disorder in Pregnancy and the Postpartum Period: Predictors of Morbidity https://ClinicalTrials.gov/show/NCT00580268 Completed Massachusetts General Hospital 2010-12-31
NCT00543088 Effectiveness of Anti-Psychotic in GPs Setting https://ClinicalTrials.gov/show/NCT00543088 Completed AstraZeneca NA
NCT00538629 Noninterventional Study in Bipolar Disorder and Schizophrenia With Zeldox https://ClinicalTrials.gov/show/NCT00538629 Completed Pfizer 2008-04-30
NCT00538122 Changes in Heart Rhythms Associated With Antipsychotic Drug Treatment https://ClinicalTrials.gov/show/NCT00538122 Completed Vanderbilt University 2008-07-31
NCT00533260 A Non-interventional Naturalistic Project to Investigate the Effect of the Use of SMS Text Service on Treatment Adherence in Patients Treated With Seroquel® (Quetiapine) https://ClinicalTrials.gov/show/NCT00533260 Completed AstraZeneca 2008-04-30
NCT00523601 Quetiapine Efficacy in Bipolar Depression Study https://ClinicalTrials.gov/show/NCT00523601 Completed AstraZeneca 2007-10-31
NCT00510211 An Observational Study of Olanzapine Coated and Orodispersible Tablets Effectiveness in Schizophrenic and Bipolar Outpatients. https://ClinicalTrials.gov/show/NCT00510211 Completed Eli Lilly and Company NA
NCT00472615 Menstrual Effects On Mood Symptoms in Bipolar Disorder https://ClinicalTrials.gov/show/NCT00472615 Completed University of Pittsburgh 2008-06-30
NCT00460226 Lamictal Bipolar Observational Study https://ClinicalTrials.gov/show/NCT00460226 Completed GlaxoSmithKline 2007-12-31
NCT00454883 Non-interventional Study of Ziprasidone in the Treatment of Bipolar and Schizoaffective Disorders. https://ClinicalTrials.gov/show/NCT00454883 Completed Pfizer 2007-12-31
NCT00391235 White Matter in Pediatric Bipolar Disorder: A DTI Study https://ClinicalTrials.gov/show/NCT00391235 Completed Cambridge Health Alliance 2008-09-30
NCT00382915 Measuring Smoking Behavior in People With Schizophrenia and Bipolar Disorder https://ClinicalTrials.gov/show/NCT00382915 Completed Rutgers, The State University of New Jersey 2010-09-30
NCT00365482 Bipolar Disorder in Epilepsy https://ClinicalTrials.gov/show/NCT00365482 Completed Northwell Health 2011-12-31
NCT00300820 Perspectives of Individuals With Bipolar Disorder and Siblings of Individuals With Bipolar Disorder; A Telephone Interview Study https://ClinicalTrials.gov/show/NCT00300820 Completed National Institutes of Health Clinical Center (CC) NA
NCT00264069 ADH.E.R.E.: Therapeutic ADHerence and Treatment Strategies: A Mental Health Registry https://ClinicalTrials.gov/show/NCT00264069 Completed Janssen-Cilag, S.A. NA
NCT00252577 Genetic Predictors of Lithium Response in Bipolar Disorder https://ClinicalTrials.gov/show/NCT00252577 Completed VA Office of Research and Development 2016-03-31
NCT00238576 Lamotrigine in the Treatment of Bipolar Disorder in Women of Reproductive Age https://ClinicalTrials.gov/show/NCT00238576 Completed Stanford University 2011-12-31
NCT00224276 Prevalence of Diabetes Mellitus Among Patients Treated With Atypical and Conventional Antipsychotics https://ClinicalTrials.gov/show/NCT00224276 Completed Yale University NA
NCT00216723 Efficacy and Safety of Aripiprazole in Patients With Schizophrenia or Bipolar Disorder https://ClinicalTrials.gov/show/NCT00216723 Completed Korea Otsuka Pharmaceutical Co., Ltd. NA
NCT00205933 Behavioral Processes Underlying Reward Processing in Depression https://ClinicalTrials.gov/show/NCT00205933 Completed Affective Neuroscience Laboratory NA
NCT00184418 The Immune System and Psychiatric Disorders https://ClinicalTrials.gov/show/NCT00184418 Completed Norwegian University of Science and Technology 2008-01-31
NCT00183703 Understanding Treatment Adherence Among Individuals With Rapid Cycling Bipolar Disorder https://ClinicalTrials.gov/show/NCT00183703 Completed Case Western Reserve University 2006-11-30
NCT00183495 Understanding Treatment Adherence Among Individuals With Bipolar Disorder https://ClinicalTrials.gov/show/NCT00183495 Completed Case Western Reserve University 2007-03-31
NCT00183352 Reproductive Function and Mood in Women With Bipolar Disorder https://ClinicalTrials.gov/show/NCT00183352 Completed Stanford University 2008-07-31
NCT00181831 Spectroscopy in Children and Adolescents With Bipolar Disorder https://ClinicalTrials.gov/show/NCT00181831 Completed Massachusetts General Hospital 2005-11-30
NCT00116077 Dopamine Receptor Imaging in Mood Disorders https://ClinicalTrials.gov/show/NCT00116077 Completed National Institutes of Health Clinical Center (CC) NA
NCT00024635 Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers https://ClinicalTrials.gov/show/NCT00024635 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT00050700 Brain Imaging in Depression https://ClinicalTrials.gov/show/NCT00050700 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001772 Evaluation of Patients With Rapid Cycling Bipolar Disorder (RCBD) https://ClinicalTrials.gov/show/NCT00001772 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001285 Effects of Sex Hormones on Circadian Rhythm in Men and Women https://ClinicalTrials.gov/show/NCT00001285 Completed National Institutes of Health Clinical Center (CC) NA
NCT00029640 The Treatment of Children and Adolescents With Treatment-Resistant Depression https://ClinicalTrials.gov/show/NCT00029640 Completed National Institutes of Health Clinical Center (CC) NA
NCT00026832 Examination of Brain Serotonin Receptors in Patients With Mood Disorders https://ClinicalTrials.gov/show/NCT00026832 Completed National Institutes of Health Clinical Center (CC) NA
NCT00690859 Predictors of Recurrence in Bipolar Disorder in Spain https://ClinicalTrials.gov/show/NCT00690859 Completed AstraZeneca 2009-03-31
NCT00201526 Bipolar Research And Innovation Network - BRAIN https://ClinicalTrials.gov/show/NCT00201526 Recruiting Norwegian University of Science and Technology 2030-01-31
NCT00001652 The Evaluation and Follow-up of Patients With Bipolar Disorder https://ClinicalTrials.gov/show/NCT00001652 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001544 Genetic Aspects of Neurologic and Psychiatric Disorders https://ClinicalTrials.gov/show/NCT00001544 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001170 Study of the Psychological Development of Children of Parents With and Without Affective Disorders https://ClinicalTrials.gov/show/NCT00001170 Completed National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03088657 Design and Methods of the Mood Disorder Cohort Research Consortium (MDCRC) Study https://ClinicalTrials.gov/show/NCT03088657 Recruiting Korea University Anam Hospital 2022-07-31
NCT02453438 Mood Patient Powered Research Network (MoodNetwork) https://ClinicalTrials.gov/show/NCT02453438 Completed Massachusetts General Hospital 2019-03-31
NCT02443636 The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Registry https://ClinicalTrials.gov/show/NCT02443636 Recruiting Nova Scotia Health Authority 2025-01-31
NCT02360267 Pediatric Bipolar Registry https://ClinicalTrials.gov/show/NCT02360267 Enrolling by invitation The University of Texas Health Science Center, Houston 2022-12-31
NCT01784341 Circadian Phase in Bipolar Depression: Is it Delayed and Does it Normalize With Remission? https://ClinicalTrials.gov/show/NCT01784341 Completed Northwestern University 2016-12-31
NCT04359628 How Does Patients’ Overall Assessment of Their Health Vary Across and Within Different Disease Groups? https://ClinicalTrials.gov/show/NCT04359628 Recruiting Vastra Gotaland Region 2020-09-30
NCT03977909 Early Maladaptative Schemas Among Euthymic Patients With Bipolar Disorder in the Versailles FondaMental Advanced Centers of Expertise for Bipolar Disorders Cohort https://ClinicalTrials.gov/show/NCT03977909 Recruiting Versailles Hospital 2024-07-01
NCT01246765 National Pregnancy Registry for Atypical Antipsychotics https://ClinicalTrials.gov/show/NCT01246765 Recruiting Massachusetts General Hospital 2022-12-31
NCT03595670 Illness Representations in Patients With Bipolar Disorders https://ClinicalTrials.gov/show/NCT03595670 Recruiting Assistance Publique Hopitaux De Marseille 2020-04-30
NCT04226963 A Naturalistic Study of Ketamine for Treatment Resistant Mood Disorders https://ClinicalTrials.gov/show/NCT04226963 Recruiting Medical University of Gdansk 2022-12-31
NCT00762866 Psychiatric Genotype/Phenotype Project Repository https://ClinicalTrials.gov/show/NCT00762866 Enrolling by invitation Vanderbilt University Medical Center 2020-12-31